ALTERATIONS IN THE GUT MICROBIOME IN THE PROGRESSION OF CIRRHOSIS TO HEPATOCELLULAR CARCINOMA

ABSTRACT Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related mortality worldwide.While cirrhosis is the main risk factor for HCC, the factors influencing progression from cirrhosis to HCC remain largely unknown.Gut microbiota plays a key role in liver diseases; however, its association with HCC remains elusive.This study ai